A Chicago South Loop car rental from SIXT makes exploring this vibrant city easier. Whether you’re a solo traveler or need a vehicle to fit a group, our range of car categories has something for everyone. Book an economy or full-size sedan, a minivan or an SUV. Then add on extra protection, child seats, GPS, an additional driver, Express Toll Unlimited or SIXT Connect. Your rent a car in Chicago South Loop also includes unlimited miles on standard vehicles. If you’re visiting in the warmer months, a sedan is a great choice to get around the city streets. In winter months, choose an SUV that can handle snow.