San Diego to San Francisco
One-Way rentals
San Diego to San Francisco

One-Way Car Rental

San Diego to San Francisco

See more of California with an affordable one way car rental from San Diego to San Francisco with no one way fee. A one way car rental lets you pick up a rental car in one city and return it to a different SIXT location. Book a one-way car rental deal and head off on an exciting road trip from San Diego to San Francisco, stopping at top attractions along the way. If continuing your journey from another transportation hub, make it easy and seamless with a one way car rental from San Diego to San Francisco. Whatever the occasion, count on a first class driving experience at an economy price with our one-way car rental services.

One-way Convertible Rental

A convertible rental is a fun way to enjoy the great California weather, taking in the sun and the scenery. Whether exploring the coast or having an adventure in the city driving with the top down gives you the chance to fully immerse yourself in your surroundings. Make special memories on your California road trip with the right convertible rental from Sixt.

One-way SUV Rental

Drive from San Diego to San Francisco with an SUV rental and have a vehicle that is ready for anything. Our fleet includes full-size, crossover and luxury SUV rentals so you can find the right model to fit your trip. Give yourself a perfect way to enjoy the drive with the comforts and spaciousness of an SUV rental.

One-way Luxury Car Rental

Wanting to travel California in ultimate style? Take advantage of our attractive rates on luxury car rentals and experience a first class driving experience. Our luxury car fleet features diverse vehicles from some of the best car manufacturers in the world. Make a statement while cruising the streets and choose an exotic car rental for your drive between San Diego and San Francisco.

Drive between San Diego and San Francisco with no fee!

Sixt rent a car provides affordable transportation between San Diego and San Francisco with no fee one way car rental. Make it to all the best destinations in both cities and get to see and do more with a one-way car rental. The large selection of vehicles in our premium fleet means you get to make the drive from San Diego to San Francisco with a rental car that matches your style and mobility needs. Whether it interested in driving an SUV,  sports car, convertible, or luxury car rental we can accommodate with plenty of choice. Experience everything you can while driving to your final destination and take advantage of a Sixt one way car rental deal.

Fastest route from San Diego to San Francisco

The quickest route between San Diego and San Francisco is the 502 mile drive north along Interstate 5, which takes about 8 hours. This inland route is, however, less scenic as a driving north on US Hwy 101 or directly along the California coast on Hwy 1. Driving on US 101 lengthens the drive by an hour while driving Hwy 1 turns the trip into an about 600 mile, 12 hour drive. If you do drive Hwy 1 it is best to break up the drive over two days to make sure you do not have to drive the best parts in the dark. Informing yourself ahead of your departure about any road closures due to fires or other weather conditions is also recommended.

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Scenic route from San Diego to San Francisco

If deciding to take a longer, more scenic route on your drive to San Diego to San Francisco there are lots of top destinations to make stops at along the way. From amazing nature to beautiful coastal cities there are plenty of places to stop, stretch your legs and take in the sights of California. Here are just a few suggestions:

  • Stop for lunch or a quick trip to the beach in beautiful Santa Barbara
  • Have a look at the elephant seals from mid-November to mid-January at Hearst-San Simeon State Park or visit the truly unique Hearst Castle
  • Take a hike and take in the amazing landscape of Big Sur
  • Browse the galleries and boutiques of Carmel-by-the-Sea or visit the Monterey Aquarium