In business, location is everything – especially when it comes to traveling for client meetings and conferences. Leading U.S. cities deliver not only convenience when on the go, but also access to the networks and innovation that drive growth. With mobility solutions from SIXT business, companies can ensure their teams move seamlessly as they travel for work.
With this in mind, we uncovered the 50 best U.S. cities for business travelers by analyzing various factors such as the percentage of business-focused hotels in each city, as well as the number of Fortune 500 companies, coworking locations, and networking events per 100,000 people.
The Top U.S. Cities for Business Travelers
1. Dallas, TX
Dallas tops the list as the best U.S. city for business travelers, setting the standard for where work meets opportunity. With one Fortune 500 company and about 55 conferences, trade shows, and networking events per 100,000 people, the Dallas-Fort Worth area is brimming with opportunities to connect and grow year-round.
Business travelers also benefit from a strong infrastructure: with 22 major highways that keep the city well-connected, nearly five coworking spaces per 100,000 people, and over 80% of hotels are business-focused – offering amenities like meeting rooms, business centers, and free WiFi to help keep travelers connected while away from their home office. Considering Dallas-Fort Worth International Airport is just 41 minutes away, the city itself feels like an extension of the boardroom.
2. Irving, TX
Remaining in the Lone Star State, Irving secures the second spot as the best U.S. city for business travelers. With four Fortune 500 companies and 13 coworking spaces per 100,000 people, there’s plenty of opportunity for flexible work options in the city. Business networking is booming here as well, with nearly 30 conferences, trade shows, and networking events per 100,000 people.
Additionally, 86% of the city’s hotels cater to business travelers’ needs, and with Dallas-Fort Worth International Airport only eight minutes away, traveling for work couldn’t be more convenient. With access to six major highways and robust infrastructure, Irving stands out as a powerhouse hub for business travel – firmly establishing it as the second-best city in Texas for business travelers.
3. St. Louis, MO
Thanks to its balance of accessibility and professional opportunities, St. Louis earns the third spot among the best U.S. cities for business travelers. With three Fortune 500 companies and more than 57 conferences, trade shows, and networking events per 100,000 people, the city has no shortage of ways to build professional connections.
While there aren’t as many coworking spaces in the Gateway to the West, with around 3 per 100,000 people, St. Louis makes up for it with a strong infrastructure. 80% of the city’s hotels are business-focused, access to 12 major highways keeps the city moving, and St. Louis Lambert International Airport is only 13 minutes away from the city center. Altogether, St. Louis makes doing business while on the road efficient and convenient.
4. Washington, DC
The nation’s capital, Washington DC, ranks as the fourth best U.S. city for business travelers, standing out as a hub of influence and connectivity. With two Fortune 500 companies per 100,000 people and six major highways, the city has a strong corporate – and governmental – presence with reliable infrastructure.
It also leads the way in professional gatherings, hosting a whopping 190 conferences, trade shows, and networking events per 100,000 people throughout the year. Business travelers also benefit from over 85% of hotels catering to corporate needs, six coworking spaces per 100,000 people, and quick access to Ronald Reagan Washington National Airport just nine minutes away – delivering unmatched opportunities to connect and conduct business.
5. Atlanta, GA
Atlanta rounds out the top five best U.S. cities for business travelers. With four Fortune 500 companies and nearly six coworking spaces per 100,000 people, the city provides a strong foundation for both established businesses and those with a more flexible working style. Atlanta also shines as a hub for professional gatherings, hosting more than 156 conferences, trade shows, and networking events per 100,000 people each year.
For business travelers, Atlanta combines accessibility with opportunity, especially considering that about 72% of hotels in the area are business-focused. With Hartsfield-Jackson International Airport only nine minutes away from the city center, plus access to four major highways, getting in and out of the city is seamless.
6. Kansas City, KS
Kansas City ranks as the sixth best U.S. city for business travelers. With two Fortune 500 companies and nearly 10 coworking spaces per 100,000 people, the city supports both large-scale corporations as well as flexible, modern work environments. Business networking thrives in this Midwestern city, with more than 183 conferences, trade shows, and networking events per 100,000 people every year.
For corporate professionals on the go, Kansas City is both practical and convenient, with roughly 76% of local hotels catering to business travelers, ensuring they have the amenities they need to stay productive. The city’s connectivity is further bolstered by access to nine major highways, while Kansas City International Airport is only about a 30-minute drive from the city center, making it easy to arrive and get to work.
7. Denver, CO
Moving out west, Denver ranks as the seventh best U.S. city for business travelers. The Mile High City has one Fortune 500 company and close to 98 conferences, trade shows, and networking events per 100,000 people each year, providing countless chances to expand professional networks and build business relationships. Add in approximately seven coworking spaces per 100,000 people, and Denver caters to professionals looking for flexible, modern work environments.
In Denver, travel logistics are a breeze, with the city being connected by 13 major highways. Nearly 78% of local hotels are also business-focused, ensuring that corporate guests have the work-friendly amenities they need. Altogether, Denver combines accessibility and professional opportunities to create an ideal hub for business travelers.
8. Tempe, AZ
Staying on the West Coast, Tempe ranks as the eighth best U.S. city for business travelers. With three Fortune 500 companies and over 10 coworking locations per 100,000 people, the city supports both established businesses and more flexible work styles. Though the city only hosts about 20 conferences, trade shows, and networking events per 100,000 people each year, there’s still plenty of opportunity to make lasting connections.
Four major highways run through the city, and with Phoenix Sky Harbor International Airport just 19 minutes away, getting to and from Tempe is hassle-free. Approximately 88% of the city’s hotels cater to business travelers, ensuring they have access to everything they need to stay productive while on the road, making Tempe a standout destination for business travel in the Southwest.
9. Pittsburgh, PA
Pittsburgh takes the ninth spot among the best U.S. cities for business travelers. The Steel City has three Fortune 500 companies and just about 70 conferences, trade shows, and networking events per 100,000 people annually, providing many opportunities for business development. Flexible work options are also present, with over five coworking spaces per 100,000 residents available throughout the city.
Nearly 78% of hotels in the area are geared toward business travelers, offering all the services needed to stay productive while away from the office. The city is also supported by eight major highways, while Pittsburgh International Airport is about a 24-minute drive from downtown – making Pittsburgh a convenient location for business professionals on the move.
10. Arlington, TX
Arlington rounds out the top 10 best U.S. cities for business travelers and marks the third Texas city to make the top 10 ranking, highlighting the Lone Star State’s strength as a hub for corporate travel. The city’s mix of three Fortune 500 companies and more than 11 coworking spaces per 100,000 people demonstrates the city’s ability to serve both large-scale businesses and flexible workforces. Though the city doesn’t currently host many conferences, trade shows, or networking events, its proximity to Dallas and Fort Worth means business travelers can still benefit from the region’s thriving professional scene.
The city is connected by five major highways, making travel across the metro area simple, especially with Dallas-Fort Worth International Airport 19 minutes away. Approximately 81% of Arlington’s hotels provide reliable amenities to keep professionals productive on the go, adding to Texas’s growing reputation as a business travel powerhouse.
| Ranking | City | State | Population | Number of Fortune 500 companies headquartered per 100k people | Number of major highways | Proximity to nearest international airport (in minutes) | Number of Coworking locations per 100k people | Number of conferences, trade shows, and networking events per 100k people | % of Business-focused hotels |
|---|---|---|---|---|---|---|---|---|---|
1 | Dallas | Texas | 1,302,638 | 1.6 | 22 | 41 | 4.68 | 54.58 | 80.76% |
2 | Irving | Texas | 252,750 | 4.4 | 6 | 8 | 13.06 | 29.67 | 85.63% |
3 | St. Louis | Missouri | 269,259 | 3.7 | 12 | 13 | 2.60 | 57.19 | 80.33% |
4 | Washington D.C. | District of Columbia | 684,394 | 2.9 | 6 | 9 | 5.55 | 189.95 | 84.87% |
5 | Atlanta | Georgia | 518,107 | 4.4 | 4 | 9 | 5.79 | 156.34 | 72.13% |
6 | Kansas City | Kansas | 150,689 | 2.0 | 9 | 31 | 9.95 | 183.16 | 76.42% |
7 | Denver | Colorado | 715,891 | 1.8 | 13 | 17 | 6.57 | 98.48 | 77.71% |
8 | Tempe | Arizona | 192,838 | 3.6 | 4 | 19 | 10.37 | 19.71 | 87.50% |
9 | Pittsburgh | Pennsylvania | 303,572 | 3.0 | 8 | 24 | 5.27 | 69.51 | 78.19% |
10 | Arlington | Texas | 401,219 | 3.3 | 5 | 19 | 11.12 | 0.00 | 80.60% |
11 | Orlando | Florida | 329,347 | 1.2 | 8 | 24 | 5.77 | 345.84 | 63.04% |
12 | Scottsdale | Arizona | 246,068 | 2.8 | 1 | 19 | 17.07 | 93.47 | 77.09% |
13 | Minneapolis | Minnesota | 421,385 | 1.7 | 5 | 153 | 4.75 | 131.71 | 86.80% |
14 | Houston | Texas | 2,324,082 | 1.5 | 12 | 16 | 2.62 | 26.68 | 77.09% |
15 | Cleveland | Ohio | 356,556 | 2.5 | 7 | 14 | 1.68 | 44.03 | 81.05% |
16 | Arlington | Virginia | 242,900 | 2.2 | 6 | 28 | 3.49 | 12.71 | 88.89% |
17 | Birmingham | Alabama | 194,156 | 1.5 | 11 | 21 | 3.09 | 101.98 | 69.47% |
18 | Bellevue | Washington | 151,436 | 2.0 | 3 | 32 | 5.94 | 40.94 | 93.75% |
19 | Richmond | Virginia | 230,787 | 3.5 | 4 | 81 | 2.17 | 37.70 | 73.14% |
20 | New York City | New York | 7,936,530 | 0.8 | 17 | 24 | 1.81 | 14.79 | 64.15% |
21 | Alexandria | Virginia | 152,624 | 0.0 | 10 | 29 | 4.59 | 24.90 | 93.33% |
22 | Cincinnati | Ohio | 312,094 | 1.9 | 7 | 9 | 2.88 | 35.89 | 79.22% |
23 | St. Paul | Minnesota | 298,940 | 1.7 | 5 | 62 | 3.68 | 22.75 | 87.80% |
24 | Sunnyvale | California | 149,778 | 2.7 | 2 | 25 | 8.68 | 4.67 | 80.95% |
25 | Columbus | Ohio | 917,679 | 1.5 | 7 | 17 | 1.31 | 34.11 | 81.48% |
26 | Chicago | Illinois | 2,611,867 | 0.9 | 10 | 12 | 1.84 | 44.60 | 76.48% |
27 | Boston | Massachusetts | 639,411 | 0.5 | 7 | 19 | 5.79 | 118.55 | 78.13% |
28 | Corpus Christi | Texas | 315,615 | 0.0 | 5 | 50 | 29.47 | 3.49 | 72.28% |
29 | Charlotte | North Carolina | 935,017 | 1.5 | 5 | 154 | 2.03 | 21.60 | 83.99% |
30 | Kansas City | Missouri | 512,360 | 0.6 | 9 | 21 | 3.12 | 53.48 | 76.39% |
31 | Jersey City | New Jersey | 291,462 | 0.7 | 3 | 87 | 14.07 | 95.72 | 76.92% |
32 | North Las Vegas | Nevada | 300,475 | 0.0 | 5 | 11 | 2.00 | 348.12 | 66.67% |
33 | Milwaukee | Wisconsin | 550,837 | 1.5 | 6 | 10 | 3.09 | 22.33 | 77.71% |
34 | Nashville | Tennessee | 686,513 | 0.4 | 8 | 15 | 2.91 | 80.70 | 77.33% |
35 | Detroit | Michigan | 629,830 | 0.8 | 9 | 15 | 2.22 | 20.32 | 76.69% |
36 | Charleston | South Carolina | 158,367 | 0.0 | 10 | 15 | 3.79 | 54.30 | 77.50% |
37 | Indianapolis | Indiana | 874,037 | 0.7 | 7 | 11 | 1.37 | 51.71 | 80.53% |
38 | Salt Lake City | Utah | 215,548 | 0.9 | 4 | 15 | 5.57 | 76.55 | 79.66% |
39 | Grand Rapids | Michigan | 195,208 | 1.0 | 4 | 21 | 3.07 | 112.70 | 77.17% |
40 | Chattanooga | Tennessee | 190,671 | 0.5 | 13 | 105 | 0.52 | 24.13 | 65.10% |
41 | Louisville | Kentucky | 617,027 | 1.0 | 6 | 31 | 0.97 | 42.46 | 79.76% |
42 | Memphis | Tennessee | 607,581 | 0.8 | 10 | 20 | 0.82 | 12.18 | 71.35% |
43 | Seattle | Washington | 764,753 | 1.0 | 5 | 19 | 3.79 | 54.00 | 77.24% |
44 | Glendale | Arizona | 257,125 | 0.0 | 2 | 9 | 1.94 | 274.96 | 78.91% |
45 | Madison | Wisconsin | 283,705 | 1.8 | 3 | 32 | 4.23 | 82.48 | 70.30% |
46 | Fort Worth | Texas | 1,015,045 | 0.3 | 8 | 30 | 3.25 | 11.03 | 80.45% |
47 | Newark | New Jersey | 301,170 | 1.3 | 6 | 17 | 1.66 | 2.66 | 76.47% |
48 | Boise | Idaho | 235,012 | 1.3 | 5 | 14 | 2.13 | 39.15 | 75.61% |
49 | Little Rock | Arkansas | 204,647 | 1.0 | 5 | 26 | 0.49 | 40.07 | 80.73% |
50 | Tulsa | Oklahoma | 410,722 | 1.2 | 6 | 49 | 2.43 | 11.93 | 74.80% |
Business Travel Made Seamless
From Dallas to Arlington and beyond, these top cities highlight how the right environment can make corporate travel more productive, efficient, and connected. Each destination offers its own advantages – whether it’s coworking access, proximity to major airports, or networking opportunities – ensuring business travelers can focus less on the logistics of their trip, but on the career-building opportunities that lie ahead of them.
With SIXT business, you can ensure your team’s travel is made seamless with a wide selection of intermediate and premium vehicles, mid-week availability, electronic invoicing, and digital account services, including our counter by-pass product Mobile Check-In and the convenience of booking via SIXT.com and the SIXT app.
To find the best U.S. cities for business travelers, we identified a list of the 50 most populous U.S. cities. We then analyzed the number of Fortune 500 companies, coworking locations, and conferences/trade shows/networking events per 100k people. Using Google Maps, we then analyzed access to major highways and proximity to the nearest international airport. Finally, we determined the percentage of business-focused hotels for each city listed to determine our ranking. Data accurate as of August 25, 2025.
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