Car rental in Panama

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Places to start your journey in Panama

Most popular in Panama

* The prices were calculated on 06/01/2023 for a 4 days prepaid rental at Tocumen International Airport starting on 06/08/2023. Our prices fluctuate daily and this offer is not guaranteed.

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Car Rental in Panama

Car Rental in Panama

Car rental in Panama is made easy when you choose SIXT. We offer plenty of locations in Panama including those in urban centers like Panama City, and at major airports. Our branches offer convenient hours, with some locations offering 24-hour service. You can choose from a vast range of car categories and find something to meet your needs. Our branch staff also speaks English to better assist you with your rental. If you have bulky items to haul on your trip, choose a pickup truck. Or if you are traveling with a group, book a roomy passenger van.
SIXT Services in Panama

SIXT Services in Panama

For those in need of car rental in Panama, SIXT is the answer. When you rent a car in Panama with us, you can choose from a variety of car categories including compact cars, sedans and SUVs. Add prepaid fuel to your rental to save time and money. Or add GPS and an additional driver to make your trip more comfortable. Whether you need a one-day rental or a weekly rental, SIXT is ready to meet all your rental car needs.
Best places to visit in Panama

Best places to visit in Panama

  • Panama Canal: This is certainly one of the most famous landmarks in Panama and known throughout the world. The canal makes its way from Panama City on the Pacific Ocean to Colon on the Caribbean Sea. This marvel of engineering is a must-see for visitors.
  • Panama City: This is the largest city in Panama, and its capital. It is quite often regarded as one of the most modern cities in Central America and in fact many people refer to it as the Dubai of Latin America. Visitors here will find all manner of luxury shopping malls, high-end resorts and magnificent skyscrapers dotting the landscape.
  • *Bocas del Toro: *This is a cluster of islands and keys that sit between Amarante Bay and Chriqui Lagoon on the Caribbean Sea. This is a great place to do some exploring via either water taxis or private boats. In addition, Isla Colon offers access by ferry or plane. Explorers in this area will find several wild jungles and national parks with all manner of plant and animal life to see.
Summer in Panama

Summer in Panama

Because Panama lies so close to the equator, you'll find the weather is much the same in both summer and winter. No matter when you visit Panama you will find that you are spending a lot of time outdoors. Visitors that come here during the summer are usually heading to the amazing beaches, partaking in water sports or trying out Panama’s amazing hiking trails.
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Good to know when renting in Panama

Accepted payment methods

We accept all major credit cards in the renter’s name. Prepaid and debit cards as well as cash cannot be used for payment.

One-way car rental in Panama

We allow one-way rentals between SIXT stations in Panama, depending on the rate. An additional fee may apply.

Cross-border travel

You are not allowed to take your SIXT rental in Panama into neighboring countries.

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The way to Sixt
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Long Term Rental

Long Term Rental

Rent a car for a longer period and save.


Get everything you need from car seats to prepaid tolls.
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FAQs about rentals in Panama

Flexible rental options
Documents you need to rent a car in Panama
Car rental under 25 in Panama
What's the minimum age to rent a car in Panama?
Can I modify, extend, or cancel my reservation?
What documents do I need to rent a car in Panama?
Can I book a long-term car rental in Panama?
Do I need to purchase insurance or protection packages with my rental in Panama?

Explore our car rental locations in Panama

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